A randomized placebo-controlled trial of oxybutynin for the initial treatment of palmar and axillary hyperhidrosis

Wolosker N, de Campos JRM, Kauffman P, et al (Univ of São Paulo Med School and Hosp Albert Einstein, Brazil) J Vasc Surg 55:1696-1700, 2012^§

Abstract

Introduction

Video-assisted thoracic sympathectomy provides excellent resolution of palmar and axillary hyperhidrosis but is associated with compensatory hyperhidrosis. Low doses of oxybutynin, an anticholinergic medication that competitively antagonizes the muscarinic acetylcholine receptor, can be used to treat palmar hyperhidrosis with fewer side effects.

Objective

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