PPAR Gamma Receptor, Skin Lipids and Hair




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Chene G, et al. n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells. Biochim Biophys Acta. 2007;1771(5):576–89.PubMedCrossRef


Dai X, et al. STAT5a/PPARgamma pathway regulates involucrin expression in keratinocyte differentiation. J Invest Dermatol. 2007;127(7):1728–35.PubMed


Dai X, et al. PPAR gamma is an important transcription factor in 1 alpha, 25-dihydroxyvitamin D3-induced involucrin expression. J Dermatol Sci. 2008;50(1):53–60.PubMedCrossRef


Dai X, et al. PPARgamma mediates innate immunity by regulating the 1alpha, 25-dihydroxyvitamin D3 induced hBD-3 and cathelicidin in human keratinocytes. J Dermatol Sci. 2010;60(3):179–86.PubMedCrossRef


Demerjian M, et al. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Exp Dermatol. 2006;15(3):154–60.PubMedCrossRef


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Downie MM, et al. Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro. Br J Dermatol. 2004;151(4):766–75.PubMedCrossRef


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Ellis CN, et al. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Arch Dermatol. 2000;136(5):609–16.PubMedCrossRef


Ellis CN, et al. Placebo response in two long-term randomized psoriasis studies that were negative for rosiglitazone. Am J Clin Dermatol. 2007;8(2):93–102.PubMedCrossRef


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Fang F, et al. The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy. Arthritis Res Ther. 2012;14(5):R229.PubMedCentralPubMedCrossRef


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Festa E, et al. Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell. 2011;146(5):761–71.PubMedCentralPubMedCrossRef


Flori E, et al. 2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-gamma activation. Pigment Cell Melanoma Res. 2011;24(4):618–30.PubMedCrossRef


Fu G, et al. Committed differentiation of hair follicle bulge cells into sebocytes: an in vitro study. Int J Dermatol. 2010;49(2):135–40.PubMedCrossRef


Ghosh AK, et al. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum. 2004;50(4):1305–18.PubMedCrossRef


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Oct 15, 2016 | Posted by in Dermatology | Comments Off on PPAR Gamma Receptor, Skin Lipids and Hair

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