A 35-year-old woman was diagnosed with pemphigus vulgaris (PV) a year ago and has been under treatment with 55 mg/day of prednisone and mycophenolate mofetil . She has had several disease recurrences when she was on 10 mg/day of prednisone and when she was on 15 mg/day of prednisone. Currently she is under treatment with 7.5 mg/day of prednisone and 15 mg/week of methotrexate .