of nerve defect with acellular nerve graft supplemented by bone marrow stromal cells in mice

Peripheral Nerve Injury and Repair


Repair of nerve defect with acellular nerve graft supplemented by bone marrow stromal cells in mice


Zhao Z, Wang Y, Peng J, et al (General Hosp of Chinese PLA, Beijing, People’s Republic of China) Microsurgery 31:388-394, 2011§



J. Isaacs, MD



Evidence Ranking


• B



Expert Rating


• 2



Abstract


The acellular nerve graft that can provide internal structure and extracellular matrix components of the nerve is an alternative for repair of peripheral nerve defects. However, results of the acellular nerve grafting for nerve repair still remain inconsistent. This study aimed to investigate if supplementing bone marrow mesenchymal stromal cells (MSCs) could improve the results of nerve repair with the acellular nerve graft in a 10-mm sciatic nerve defect model in mice. Eighteen mice were divided into three groups (n

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Apr 2, 2016 | Posted by in Hand surgery | Comments Off on of nerve defect with acellular nerve graft supplemented by bone marrow stromal cells in mice

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