Melanoma represents 4% of all cancers in men and 3% of all cancers in women. This innocuous pigmented lesion on the nose was shown to be lentigo maligna on biopsy.

It cannot be overemphasized that melanomas vary considerably—no single color or change is diagnostic. This melanoma has areas of inflammation (red), regression (white), and deeper pigment (blue).

Lesions tend to be greater than 6 mm in diameter, flat, and asymmetric, with varying coloration. This advanced lesion shows ulceration.