Injection as Nonsurgical Treatment of Dupuytren’s Disease: 8-Year Follow-Up

Dupuytren’s Contracture


Collagenase Injection as Nonsurgical Treatment of Dupuytren’s Disease: 8-Year Follow-Up


Watt AJ, Curtin CM, Hentz VR (Stanford Univ Hosps and Clinics, Palo Alto, CA) J Hand Surg 35A:534-539, 2010§



S.K. Lee, MD



Evidence Ranking


• B



Expert Rating


• 2



Abstract



Purpose


Collagenase has been investigated in phase II and phase III clinical trials for the treatment of Dupuytren’s disease. The purpose of this study is to report 8-year follow-up results in a subset of patients who had collagenase injection for the treatment of Dupuytren’s contracture.



Methods


Twenty-three patients who participated in the phase II clinical trial of injectable collagenase were contacted by letter and phone. Eight patients were enrolled, completed a Dupuytren’s disease questionnaire, and had independent examination of joint motion by a single examiner.



Results

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Apr 2, 2016 | Posted by in Hand surgery | Comments Off on Injection as Nonsurgical Treatment of Dupuytren’s Disease: 8-Year Follow-Up

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