Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children

Trauma


Burns


Randomized Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children


Branski LK, Herndon DN, Barrow RE, et al (Univ of Texas Med Branch and Shriners Hosps for Children, Galveston) Ann Surg 250:514-523, 2009§



R.E. Salisbury, MD



Evidence Ranking


• A



Expert Rating


• 3



Abstract



Background


Recovery from a massive burn is characterized by catabolic and hypermetabolic responses that persist up to 2 years and impair rehabilitation and reintegration. The objective of this study was to determine the effects of long-term treatment with recombinant human growth hormone (rhGH) on growth, hypermetabolism, body composition, bone metabolism, cardiac work, and scarring in a large prospective randomized single-center controlled clinical trial in pediatric patients with massive burns.



Patients and Methods

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Mar 5, 2016 | Posted by in Aesthetic plastic surgery | Comments Off on Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children

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