Scars and Wound Healing

Wound Healing

Randomized clinical trial of Chinese herbal medications to reduce wound complications after mastectomy for breast carcinoma

Chen J, Lv Q, Yu M, et al (Sichuan Univ, China; et al) Br J Surg 97:1798-1804, 2010^§

Abstract

Background

Ischaemia and necrosis of skin flaps is a common complication after mastectomy. This study evaluated the influence of anisodamine and Salvia miltiorrhiza on wound complications after mastectomy for breast cancer.

Methods

Ninety patients undergoing mastectomy for breast carcinoma were divided into three groups. Group 1 received routine wound care, group 2 received intravenous Salvia miltiorrhiza after surgery for 3 days and group 3 similarly received intravenous anisodamine. Skin flaps were observed on postoperative days 4 and 8; areas of wound ischaemia and necrosis were graded and adverse events recorded.

Results

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