Figure 32.1
Scabies, extremely pruritic papules in a widespread pattern
Clinical Differential Diagnosis
Drug eruption
Scabies
Bedbugs
Atopic dermatitis
Contact dermatitis
Urticaria stage of bullous pemphigoid
Histopathology
The first biopsy was from the trunk which showed spongiotic dermatitis, but no insect body was seen. A second biopsy was taken which showed features of an insect bite, and negative results for fungus in the Periodic Acid-Schiff stain. A third biopsy was taken from the trunk and extremities which did show an insect residing within the cornified layer (Fig. 32.2).
Figure 32.2
H&E 400 × Scabies mite cross-section of mite within a burrow