Case 57 Peripheral Nerve Injury



W. Kelsey Snapp and Reena A. Bhatt

Case 57 Peripheral Nerve Injury

Case 57 A 28-year-old female presents to the clinic after sustaining a laceration to her right forearm 2 days ago. She was initially seen in the emergency department after punching a mirror, where the wound was washed out and skin repaired. She describes numbness in her thumb, and index and middle fingers as well as weakness in the hand.



57.1 Description




  • Laceration repair over the volar aspect of the mid-forearm with decreased sensation to the median nerve distribution




    • Concerning for sharp injury to the median nerve



57.2 Work-Up



57.2.1 History




  • Mechanism of injury: Closed versus open




    • Closed injuries: Best treated initially with observation to distinguish between neuropraxia and true neurotmesis



    • Open injuries with nerve deficits: One must assume there is a nerve transection, requiring operative exploration and repair



  • Time since injury




    • Early repair of injured nerve is associated with improved recovery



  • Any additional or associated injuries and limitation in motion



  • Significant bleeding at the time of injury



  • Hand dominance, occupation, smoking history, and comorbidities



57.2.2 Physical Examination




  • Assess for associated lacerations, scars, presence of open injury, and viability of soft tissue coverage



  • Complete sensory examination, including two-point discrimination of ulnar, median, and radial nerves; assess motor nerve function in a controlled manner




    • Median nerve at this level innervates the flexor pollicis brevis, opponens pollicis, abductor pollicis brevis, and radial two lumbricals (index and long)




      • Ask patient to oppose thumb or flex at metacarpophalangeal (MCP) joints of index and long fingers



    • Ulnar nerve innervates the hypothenar musculature and interossei (abduct and adduct fingers, assess for clawing, Wartenberg’s sign, Froment’s sign)



  • Vasomotor paralysis is a subtle yet reliable sign of early nerve injury; the skin in the area of the affected nerve is often warm and dry



  • Tinel’s sign: May help in identifying the site and level of injury, as well as the presence of neuroma or neuroma-in-continuity



  • Palpation and Doppler evaluation of ulnar and radial arteries



  • Examine tenodesis and cascade



  • Independently examine wrist flexors and finger flexors



57.2.3 Pertinent Imaging or Diagnostic Studies




  • Standard three-view x-rays should be obtained to assess for fracture or foreign body



  • For a closed injury, electrodiagnostic studies at 3 months may be helpful in ascertaining prognosis of nerve recovery




    • Fibrillation: Indicate some degree of motor injury



    • Motor unit potentials (MUPs): Indicate recovery



57.3 Patient Counseling




  • Nerve recovery after closed or open injury takes time. Axonal regeneration occurs at a rate of approximately 1 mm/day.




    • Recovery time can be estimated by measuring the distance from the site of injury to the distal target.



  • Nerve recovery after repair is unpredictable. Successful functional recovery after peripheral nerve repair has been reported to be between 50 and 80%, depending on the nerve and the location of injury.



57.4 Treatment




  • Indications for operative exploration of a nerve




    • Paralysis/sensory deficits of a major nerve after an open wound



    • Paralysis/sensory deficits affecting a nerve after a nearby iatrogenic surgery



    • A nerve lesion associated with arterial injury



    • A nerve lesion associated with a fracture or dislocation requiring open reduction and internal fixation (e.g., radial nerve exploration after open humeral fracture)



    • Deterioration/failure of recovery of a closed nerve injury while under observation



    • Exploration for other injuries (i.e., tendon lacerations)



  • Initial treatment plan should be based on type (open vs. closed) and chronicity of nerve injury




    • Muscle denervation begins to take place soon after nerve injury and the potential for reinnervation decreases as time passes (approximately 1% per week)



    • The time needed for nerve regeneration (1 mm/day) should be weighed against the potential for muscle reinnervation when considering nerve repair



  • All patients will benefit from hand therapy to maintain passive range of motion, manage pain, edema, and other problems associated with the inciting injury



57.4.1 Acute Open Injuries with Nerve Dysfunction




  • Require nerve exploration: Must assume the nerve was transected



  • The prognosis of nerve recovery is directly related to the interval between injury and nerve repair; clean injuries to motor nerves are best treated within a few days



  • Local contamination should be considered when considering nerve repair; nerve repair should be delayed until the wound bed is clean



  • Direct repair or repair with an interposition graft is appropriate



  • Nerve transfers and babysitter procedures can be considered in high (proximal) motor nerve injuries

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Jul 17, 2021 | Posted by in General Surgery | Comments Off on Case 57 Peripheral Nerve Injury

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